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Postdoctoral positions are available in the laboratory of , Department of Pathology at UT Southwestern Medical Center to study metastatic dormancy and recurrences in breast, lung and renal adenocarcinomas. is focused on developing improved diagnostic and therapeutic modalities for treating residual disease and metastasis. We employ molecular, biochemical, immunologic, genomic, imaging and computational based techniques to understand the biology of latent and overt metastasis in breast and kidney cancers using mouse models, xenografts and patient samples.
Recent Publications:
Metabolic adaptations of brain metastasis. Nature Reviews Cancer, 2025.
AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer. Cancer Research, 2024.
Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases. Nature Cancer, 2023.