πŸ‡ΊπŸ‡Έ USAJobs.work

America's Job Portal

← Back to USA Jobs

Principal Computational Scientist, Discovery Chemistry

Company

Genentech, Inc

Location

South San Francisco, California

Posted

June 22, 2026

Position Overview

The Opportunity

We are seeking an exceptional computational scientist to apply cutting-edge computational science, focussing on peptide therapeutic discovery. The ideal candidate will possess a unique blend of expertise in computational chemistry, including machine learning, to drive the advancement of our peptide hits to clinical candidates. This is a critical strategic role aimed at accelerating our discovery pipelines, optimizing our lead candidates, and unlocking the full potential of our experimental data.

Key Responsibilities

  • Advanced Modeling & Prediction: Lead the development and implementation of advanced computational methods (structure-based, physics-based) for target and peptide modeling and optimization. Implement machine learning models to accurately predict critical peptide properties such as solubility, permeability, stability, immunogenicity, and potency.

  • Platform Development: Contribute to the design, development, ...

  • Ready to Apply?

    Join thousands of Americans building their careers

    Apply Now