The Division of Infectious Diseases at Massachusetts General Hospital is at the forefront of innovative clinical trials. In 2020, recognizing the need for a dedicated infrastructure, they established the Infectious Diseases Clinical Research Unit (ID CRU), led by Dr. Boris Juelg, Dr. Arthur Kim, and Diane Kanjilal, FNP. This unit serves as a vital support system, facilitating a myriad of innovative clinical trial projects led by accomplished investigators within the division. Under the stewardship of the Chief of Infectious Diseases, Dr. Ruanne Barnabas, the ID CRU has expanded its international research footprint. Dr. Barnabas brings a wealth of experience, having successfully concluded numerous international clinical trials that have catalyzed policy changes in various regions of Africa, notably addressing challenges in HPV and HIV access to care. In the year ahead, we look forward to implementing a clinical...