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Senior Scientist I

Company

Merck

Location

South San Francisco, CA

Posted

July 18, 2026

Position Overview

**Job Description**

**Position Summary**

We are seeking a highly motivated Senior Scientist to join our Protein Expression and Purification group at our South San Francisco site. The successful candidate will play a crucial role in the discovery of novel therapeutics through design and execution of biologics and protein expression activities with a primary focus on mammalian systems. The successful candidate will bring deep expertise in recombinant biologics production including monoclonal antibodies, multispecific scaffold and novel protein modalities particularly in CHO and HEK293 systems and will contribute to advancing discovery-stage biologics programs.

**Key Responsibilities**

· Design, execute, and optimize recombinant protein expression workflows in mammalian systems (e.g., CHO, HEK293), including transient and stable expression.

· Develop and implement strategies to improve protein yield, quality, and scalability for...

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