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Senior Scientist, NGS Profiling & Expression

Company

Merck

Location

South San Francisco, CA

Posted

July 15, 2026

Position Overview

**Job Description**

The Profiling & Expression department within Translational Medicine helps bridge Discovery and Development programs in multiple therapeutic areas through expertise in multimodal molecular analysis of tissues and model systems. We are a platform-based functional group leveraging a close partnership of pathologists, gene expression scientists, image analysis specialists, assay developers and data scientists to contribute to target validation, generation of quality mechanistic data, and the discovery and development of response and PD biomarkers with line of sight to the clinic. The Molecular Profiling group, within the Profiling & Expression department, provides key work for understanding: target tissue distributions in normal and diseased tissues, characterization of preclinical model systems, mechanism of action and proof of biology for candidate therapeutics, and drug response prediction.

The Molecular Profiling Senior Scientist will work primaril...

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