**Job Description**

The Variant Curator supports genomic analysis for patients with complex, unsolved medical conditions. The Variant Curator will be responsible for curation, interpretation, and prioritization of variants identified through whole exome sequencing (WES) and whole genome sequencing (WGS), contributing to multidisciplinary diagnostic efforts. This position requires close collaboration with the Mount Sinai Center for Undiagnosed Diseases clinical team and presentation of prioritized findings at monthly internal case review meetings. The Variant Curator is expected to analyze approximately 50 cases per year.

**Qualifications**

+ Advanced degree (MS, PhD, MD, or equivalent experience) in genetics, genomics, molecular biology, or related field.
+ Demonstrated experience in clinical or research-based variant interpretation
+ Familiarity with ACMG/AMP variant classification guidelines, use of genomic databases (e.g., ClinVar, gnomAD), and in-si...